This event brings together EMBL and EMBL Australia Partner Laboratory Network scientists with the aim to present exciting scientific research, enable exchange of expertise and provide a platform to develop and facilitate collaborative activities.

Day 1 - Wednesday, 19 September 2018
TimeSpeaker
13:40 – 13:45

Welcome
Silke Schumacher, EMBL Director International Relations

13:45 - 14:00

Introduction to EMBL Australia Partner Laboratory Network
James Whisstock, Scientific Head of EMBL Australia

Session 1: Molecular and Cellular Imaging
Chair: Jan Korbel

14:00 – 14:20

Solving a 3D jigsaw with 1000 pieces
Martin Beck, EMBL Heidelberg

14:20 – 14:40

Spatial metabolomics
Theodore Alexandrov, EMBL Heidelberg

14:40 – 15:00

Imaging inside living tissue: state-of-the-art and open challenges
Robert Prevedel, EMBL Heidelberg

15:00 – 15:20

Mechanobiology of cytotoxic T cell and tumour cell movements and interactions
Maté Biro, EMBL Australia, University of New South Wales, Sydney

15:20 – 15:40

High-throughput superresolution microscopy of endocytosis - Linking molecular architecture and mechanics of a protein machinery
Jonas Ries, EMBL Heidelberg

15:40 – 16:00

The Electron Microscopy Core Facility at EMBL: offering access to cutting edge methods for sub cellular imaging
Yannick Schwab, EMBL Heidelberg

16:00 – 16:30

Coffee break |Operon Foyer

Session 2: Transcription Regulation and RNA Biology
Chair: Edwina McGlinn

16:30 – 16:50

Dynamics and function of histone variant H3.3 in embryonic stem cells and neurons
Kyung-Min Noh, EMBL Heidelberg

16:50 – 17:10

Mechanism for RNA-mediated regulation of the histone methyltransferase polycomb repressive complex 2 (PRC2)
Chen Davidovich, EMBL Australia, Monash University, Melbourne

17:10 – 17:30

Regulatory complexity in mammalian transcriptional regulation
Paul Flicek, EMBL EBI

17:30 – 17:50

Regulatory Expansion in Mammals of Multivalent hnRNP Assemblies that Globally Control Alternative Splicing
Robert Weatheritt, EMBL Australia, Garvan Institute of Medical Research, Sydney

17:50 – 18:10

NMR and small-angle scattering for structural biology of protein-RNA complexes
Janosch Hennig, EMBL Heidelberg

18:10 – 18:30

Protein stability in drug discovery and molecular biology
Mikhail Savitzki, EMBL Heidelberg

Day 2 - Thursday, 20 September 2018
TimeSpeaker
Session 3: Cell Biology
Chair: Chen Davidovich
09:00 – 09:20

Role and regulation of YAP/TAZ in development and cancer
Barry Thompson, EMBL Australia, Australian National University, Canberra

09:20 – 9:40

Mechanics of cellular signaling
Alba Diz-Muñoz, EMBL Heidelberg

09:40 – 10:00

Optical control of cellular signals
Harald Janovjak, EMBL Australia, Australian Regenerative Medicine Institute (ARMI), Monash University, Melbourne

10:00 – 10:20 Structural studies on complement-related immune effectors
James Whisstock, EMBL Australia, Monash University
10:20 – 10:40

Importance of protein trafficking and complex formation in astrocyte cell volume regulation
Pirjo Apaja, EMBL Australia, South Australian Health and Medical Research Institute (SAHMRI)/University of Adelaide, Adelaide

10:40 – 11:10

Coffee break | Operon Foyer

Session 4: Development
Chair: Kyung-Min Noh

11:10 – 11:30

Genome regulation during developmental transitions: Generating robustness and precision
Eileen Furlong, EMBL Heidelberg

11:30 – 11:50

Breaking constraint of mammalian axial formulae
Edwina McGlinn, EMBL Australia, Australian Regenerative Medicine Institute (ARMI), Monash University, Melbourne

11:50 – 12:10

Hunting for the neural basis of emotion
Cornelius Gross, EMBL Rome

12:10 – 12:30

Decoding evolution and development: from enhancer structure to function
Justin Crocker, EMBL Heidelberg

12:30 – 14:00

Lunch | Operon Foyer

Session 5: Microbiology and Immunology
Chair: Martin Beck
14:00 – 14:20 Exploring microbiomes: From gut to ocean
Peer Bork, EMBL Heidelberg
14:20 – 14:40 T-follicular helper cells and the induction of functional anti-malarial antibodies
Michelle Boyle, EMBL Australia, QIMR Berghofer Medical Research Institute, Brisbane
14:40 – 15:00 Dissecting host-pathogen interactions using quantitative proteomics
Joel Selkrieg, EMBL Heidelberg
15:00 – 15:20 Understanding how non-ribosomal peptide synthesis builds the glycopeptide antibiotics
Max Cryle, EMBL Australia, Monash University, Melbourne
15:20 – 15:40 The impact of the microbiota in early life on infant immune responses
David Lynn, EMBL Australia, South Australian Health and Medical Research Institute (SAHMRI) /Flinders University, Adelaide
15:40 – 16:10 Coffee break | Operon Foyer
Session 6: Genomics and Molecular Medicine
Chair: David Lynn
16:10 – 16:30 From genomic variation to molecular mechanism
Jan Korbel, EMBL Heidelberg
16:30 – 16:50 Understanding principles of transcription regulation at the resolution of single DNA molecules
Arnaud Krebs, EMBL Heidelberg
16:50 – 17:10 Integrative genomics of late-onset Alzheimer’s disease and endo-lysosomal system
Ville-Petteri Mäkinen, EMBL Heidelberg, South Australian Health and Medical Research Institute (SAHMRI)/University of Adelaide, Adelaide
17:10 – 17:30 Lipid metabolism: connecting the dots
Anne-Claude Gavin, EMBL Heidelberg
17:30 – 17:50 Towards Understanding Molecular Mechanisms of Breast Cancer Treatment, Residual Disease and Recurrence
Martin Jechlinger, EMBL Heidelberg
17:50 – 18:10

Developing the next generation of growth factors and cytokines for regenerative medicine applications
Mikaël Martino, EMBL Australia, Australian Regenerative Medicine Institute (ARMI), Monash University, Melbourne

18:15 – 19:30

Closing networking reception | ATC rooftop