Keynote Lecture I
In vivo studies of human genome function
Len Pennacchio - DOE Joint Genome Institute, USA

Session 1 - Gene Regulation
Chair: Rolf Zeller

HoxA13 and HoxD13 function as pioneer factors in the developing limb
Marie Kmita - McGill University, Canada

Robustness versus evolvability: Transcriptional control of the BMP antagonist Grem1 during vertebrate limb development
Aimée Zuniga - University of Basel, Switzerland

Coffee break

Long-range gene regulation at the HoxD locus during limb development
Denis Duboule - University of Geneva, Switzerland

Two Lmx1b-associated cis-regulatory modules (LARM1/2) mediate Lmx1b auto-amplification during limb dorsalization and their disruption can cause a limb-specific form of Nail-Patella syndrome
Kerby Oberg - Loma Linda University, USA

Appropriate spatial restriction of cell signalling in the developing limb: Integration of mechanical cues
Paula Murphy - Trinity College Dublin, Ireland

Early Shh function and the late determination of digit identity:  Temporal integration by multiple signals
Susan Mackem - National Cancer Institute, USA

Meis transcription factors interpret FGF signaling gradient to convey positional information along the limb bud proximo-distal axis
Irene Delgado - Centro Nacional de Investigaciones Cardiovasculares (CNIC), Spain

Differential response of the developing limb neuromuscular system to an altered autopod pattern
Maëva Luxey - University of Basel, Switzerland

SP8-dependent regulatory network in the limb ectoderm
Marian Ros - CSIC, University of Cantabria, Spain

Regulation of the formation and maintenance of limb muscle and bone tissue
Malcolm Logan - King's College London, United Kingdom

Reprogramming non-limb fibroblasts into limb bud progenitor-like cells
Yuji Atsuta - Harvard Medical School, USA

Molecular mechanism of segmentation of limb cartilage
Amitabha Bandyopadhyay - Indian Institute of Technology Kanpur, India

Lunch

Session 3 - Patterning & Regeneration
Chair: Gregg Duester

Recruiting progenitor cells during development, wound healing, and regeneration
Joshua D. Currie - University of Toronto, Canada

Overcoming regenerative restrictions in mice
Ken Muneoka - Texas A&M University, USA

How do axolotls memorize and regulate the patterning information in limb regeneration
Akane Kawaguchi - Research Institute of Molecular Pathology (IMP), Austria

Single-cell profiling of the regenerating axolotl limb
Nicholas D Leigh - Harvard University, USA

Coffee break

Maintenance of genomic integrity in proliferating blastema cells of regenerating axolotl limbs
Jessica Whited - Harvard University, USA

EGFR activation promotes regenerative capacity in mouse digit tissue
Caroline Dealy - UConn Health, USA

Poster Session I (odd numbers)

Quantitative and comparative analysis of tissue deformation dynamics during chick and Xenopus limb development
Yoshihiro Morishita - RIKEN Center for Biosystems Dynamics Research, Japan

Biophysical approaches to morphogenesis in the mouse embryo
Sevan Hopyan - University of Toronto, Canada

Development of the pelvic girdle requires apical ectodermal ridge FGFs
Christian Louis Bonatto Paese - National Cancer Institute, USA

A new role of GDF5 in regulating cell and nuclear morphology during chondrocyte differentiation
Sarah Rubin - Weizmann Institute of Science, Israel

Lunch

Session 5 - Growth
Chair: Elazar Zelzer

The control of tempo during embryonic development: insights from limb development
Megan Davey - The University of Edinburgh, United Kingdom

Different insults to long bone growth lead to distinct scaling effects in developing mice
Alberto Roselló-Díez - Monash University, Australia

3D Visualisation of the role of cell activities in joint morphogenesis
Yuming Huang - Imperial College London, United Kingdom

Pectoral fin morphogenesis: From a monolayer to a 3D structure
Hahn Nguyen - CNRS USR3695 BioEmergences, France

Coffee break

ECM collagens in the prenatal skeletal rudiment: How do they develop and are they mechanoregulated?
Niamh Nowlan - Imperial College London, United Kingdom

Thalidomide-induced limb differences: The role of the blood vessels
Neil Vargesson - University of Aberdeen, United Kingdom

Shh mediated Fgf-signaling is compartmentalized in the mesenchyme and controls limb size during salamander development
Sruthi Purushothaman - University of Kentucky, USA

Developmental basis of mammalian limb variation
Karen E. Sears - University of California, Los Angeles, USA

What big feet you have! Development and evolution of limb skeletal proportion
Kimberly Cooper - UCSD, USA

Developmental basis of limb heterochrony in the wing of the emu (Dromaius novaehollandiae)
John Young - Harvard Medical School, USA

A developmental mechanism for metapterygial bending during the evolution of the tetrapod limb
Joost Woltering - University of Konstanz, Germany

Group photo

Left-right asymmetric reduction of skeletal elements in emu wings
Mikiko Tanaka - Tokyo Institute of Technology, Japan

Working material for appendage variation: Potential to form limb-like skeletal structures in zebrafish by activation of a latent patterning mechanism
Brent Hawkins - Harvard Medical School/Boston Children's Hospital, USA

Dissecting the cis-regulatory robustness of Ptch1 in limb development and evolution
Virginie Tissières - Centro Andaluz de Biología del Desarrollo, CSIC, Spain

Keynote Lecture III
Are Hox-expressing cells musculoskeletal stem cells?
Deneen M. Wellik - University of Wisconsin-Madison, USA